Accurate tool
ACCURATE is a software tool for quantitative analysis of (mainly) whole body PET/CT studies. The tool is developed by Ronald Boellaard (VU medical center / UMC Groningen) with input and co-development from Maqsood Yaqub (VUMC) and Floris van Velden (VUMC/LUMC). The tool is provided as a research tool only and should not be used for clinical purposes. Use of the tool is free of charge but only after consulting the primary author of the tool. The tool is continuously under development and new functionality will be added.
In case you have any questions about the ACCURATE tool, feel free to contact us or use the request form below.
If you publish any work which uses this package, please cite the following publications:
– Boellaard R. Quantitative oncology molecular analysis suite: ACCURATE [abstract]. J Nucl Med. 2018;59(suppl 1):1753.
– Burggraaff CN, Rahman F, Kassner I, et al. Optimizing workflows for fast and reliable metabolic tumor volume measurements in diffuse large B cell lymphoma. Mol Imaging Biol. 2020;22:1102–1110.
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Analysis
Analyses consists of quantification of volumes of interest (VOIs). There are different methods to obtain these VOIs:
Manually – VOIs can be manually delineated by painting voxel per voxel
Fixed size VOIs – A 2D or 3D VOI with a fixed size and shape can be placed
Semi-automated –By selecting the hottest voxel as an initial starting point, a VOI will be generated automatically using a region growing algorithm. Different thresholds are available (absolute SUV thresholds, relative SUV thresholds based on SUV peak or max, with or without background correction).
The ACCURATE tool may also be used for Metabolic Tumor Volume (MTV) analyses, where the tool already makes a preselection of the total tumor burden.
Disclaimer
For non-commercial scientific research usage only.
This tool is provided as-is, without any expressed or implied warranty. Specifically, neither the VU medical center, Amsterdam (The Netherlands) nor the authors warrant that the functions contained in the software will meet your requirements, or that the operation of the software will be uninterrupted or error-free, or that defects in the software will be corrected. To the extent permitted by law, neither the VU medical center nor the authors shall be liable for any damages arising out of or relating to the use of the software, including but not limited to incidental, special, indirect or consequential damages or any lost profits, business interruption, loss of programs or other data on your information handling system.
